Nijmegen Institute for Scientist-Practitioners in Addiction

Detoxification of patients with GHB dependence.

TitelDetoxification of patients with GHB dependence.
PublicatietypeJournal Article
Jaar van publicatie2013
Auteursvan Oene GH de Weert, Schellekens A, Dijkstra BAG, Kamal RM, DeJong CA
UitgaveTijdschr Psychiatr

BACKGROUND: A new detoxification method for ghb dependence was developed recently in the Netherlands. The method involves the use of pharmaceutical ghb.

AIM: To describe the characteristics of ghb dependent inpatients, the course of the detoxification process and patients’ progress in the three months following inpatient detoxification.

METHOD: 229 ghb dependent patients were monitored during and after inpatient detoxification. Records were kept of the psychiatric symptoms, withdrawal symptoms and relapses.

RESULTS: The average age of the patients was 29 years; 69% of the patients were male. They reported severe symptoms of co-occurring depression and anxiety. Detoxification was successful in 86% of the patients and, on a whole, the procedure ran smoothly, without complications. However, within three months following detoxification two-thirds of the patients had relapsed and were again taking ghb.

CONCLUSION: Pharmaceutical ghb can be used as an alternative to the benzodiazepine method for detoxifying patients with ghb dependence. However, the high relapse rates following detoxification are of great concern.

Alternatieve uitgaveTijdschr Psychiatr
PubMed ID24242149